Cimegripe Or Benegrip: What is it? Is it Anti-inflammatory?

Have you ever taken Benegrip or Cimegripe? These are two popular cold medicines often found in pharmacies.

In this blog post, we will discuss the differences between these two drugs, their advantages and disadvantages, and provide guidance on their use. Let’s dive in and learn more about these common cold treatments.

Benegrip: compositing and effects

Benegrip contains three main components: dipyrone, caffeine and an antihistamine called chlorpheniramine.

Dipyrone (500 mg) serves as an analgesic and antipyretic, helping to relieve pain and reduce fever. Chlorpheniramine is a first-generation antihistamine that helps relieve nasal congestion and discharge. However, this antihistamine may cause drowsiness in some patients and may thicken nasal secretions, potentially leading to sinusitis.

Finally, caffeine is included to combat fatigue and muscle pain commonly associated with colds.

Cimegripe: Composition and Effects

Cimegripe, on the other hand, contains paracetamol instead of dipyrone, making it a suitable alternative for people allergic to dipyrone. It also includes chlorpheniramine and a decongestant called phenylephrine.

Phenylephrine is a vasoconstrictor that helps relieve nasal congestion, making it particularly useful for those with severe congestion. However, it should be used with caution in patients with high blood pressure, heart problems or those taking certain medications.

Neither drug (Cimegripe or Benegrip) contains non-steroidal anti-inflammatory drugs in its formula.

Indications and Mechanism of Action

Cimegripe is indicated for the treatment of cold and flu symptoms, such as nasal congestion, runny nose, fever, headache, muscle aches and other related symptoms. It acts on the central nervous system to reduce fever and sensitivity to pain.

In addition, it blocks the release of certain substances responsible for allergic reactions, reducing symptoms such as swelling, runny nose and rhinitis, which in turn helps to relieve nasal congestion.

The effects of the medication begin approximately 15 minutes after administration.

Precautions and Recommendations

While many people turn to over-the-counter cold medications such as Benegrip or Cimegripe, it is essential to exercise caution and avoid self-medication.

It is always advisable to consult a medical professional, such as a general practitioner, otolaryngologist or pediatrician, to determine whether your cold symptoms are part of a simple viral infection or a more serious condition such as sinusitis, ear infections or pneumonia.

Keep in mind that most colds are self-limiting, lasting about 7-10 days.

During this time, the body fights off the viral infection, and medications can help manage symptoms, not cure the cold itself. Doctors often recommend treatments based on specific symptoms, such as pain relievers for headaches, anti-inflammatories for sore throats, or decongestants for nasal congestion.

possible side effects

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Like any medicine, Benegrip and Cimegripe can cause unwanted side effects. Some of the more common side effects include drowsiness, nausea, eye pain, dizziness, palpitations, dry mouth, gastrointestinal discomfort, diarrhea, tremors, and thirst.

Contraindications and risks

Cimegripe and Benegrip are contraindicated for patients with hypersensitivity to any of their components, hypertension, heart disease, diabetes, glaucoma, prostate enlargement, chronic kidney disease, severe liver failure and thyroid dysfunction.

Not to be used by pregnant women unless recommended by a doctor. Due to the multiple active substances in Cimegripe, it is generally advisable to avoid its use during pregnancy and breastfeeding. In such cases, it is preferable to use paracetamol alone for symptom relief.


In summary, Benegrip and Cimegripe are popular cold medications that target different symptoms. It is crucial to understand their differences and possible side effects before using them.

Also, always consult a healthcare professional before taking any medication, and remember that the main treatment for colds involves managing the symptoms while the body naturally fights the infection.

If you found this information helpful, please feel free to share it with friends and family and leave your questions or comments below.


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